Sustained fever resolved promptly after total thyroidectomy due to huge Hashimoto’s fibrous thyroiditis
Journal Endocrine
Publisher Humana Press Inc.
ISSN 0969-711X (Print) 1559-0100 (Online)
Issue Volume 31, Number 1 / February, 2007
Abstract
We encountered a 55-year-old female patient with Hashimoto’s thyroiditis who showed persistent fever, and could not find any source of fever other than the large nontender goiter. Her fever continued with positive CRP for 6 months. Although we did not assume that the inflammation was related to Hashimoto’s thyroiditis, total thyroidectomy was performed for cosmetic reasons; however, fever was resolved immediately after thyroidectomy.
Pathological diagnosis was Hashimoto’s chronic thyroiditis. Immunohistochemical staining showed that the follicular cells were positive for IL-1alpha, IL-1beta, and TNF-alpha.
We believed that fever was induced by inflammatory cytokines produced in thyroid. The case indicated that Hashimoto’s thyroiditis with nontender goiter could cause idiopathic fever.
I've also had thyroidits attacks lasting a while with fever.. I thought that was a part of thryoiditis, like it is with tonsillitis?, but not so severe in height of temp They've become less frequent with time...(many years on and off)